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Updated: Feb 3, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endoscopic transnasal transseptal pituitary surgery
V Favier1, J Boetto2, C Cartier1
1Service d'ORL, chirurgie maxillo-faciale et stomatologie, hôpital Gui-de-Chauliac, CHU Montpellier, 34000 Montpellier, France.
This study highlights the benefits of an entirely endoscopic transseptal transsphenoidal approach for pituitary surgery. This method offers a midline approach, a wide operative field, and fewer nasal complications.
Area of Science:
- Neurosurgery
- Endoscopic Surgery
- Pituitary Gland Disorders
Background:
- Transsphenoidal approach is the standard for pituitary surgery.
- Surgical techniques have evolved, including microscopic and endoscopic methods.
- Previous endoscopic approaches have been described since the 1990s.
Purpose of the Study:
- To describe an entirely endoscopic transseptal transsphenoidal approach.
- To evaluate the advantages of this specific surgical technique.
Main Methods:
- Utilized an entirely endoscopic transseptal transsphenoidal approach.
- Incision made in the nasal mucosa for access and tumor resection.
- Focus on a strictly midline approach to the sella turcica.
Main Results:
- Achieved a strictly midline approach to the sella turcica.
- Obtained a large operative field.
- Experienced no interference between surgical instruments.
- Reported a low rate of nasal complications.
Conclusions:
- The endoscopic transseptal transsphenoidal approach provides significant advantages.
- This technique facilitates safe and effective pituitary tumor resection.
- It offers improved surgical access and reduced postoperative nasal issues.
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