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Celiac Disease in the Pediatric Population

Jessica Durham, Heide S Temples

    Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners
    |October 29, 2018
    PubMed

    Insights

    Celiac disease is an autoimmune disorder impacting the gastrointestinal tract due to gluten. Diagnosis involves blood tests and biopsies, with a strict gluten-free diet being the only current treatment.

    Area of Science:

    • Gastroenterology
    • Immunology
    • Genetics

    Background:

    • Celiac disease is an autoimmune disorder triggered by gluten proteins.
    • It affects genetically susceptible individuals and has a high prevalence globally, particularly in North America.
    • The condition presents with diverse manifestations, complicating diagnosis.

    Purpose of the Study:

    • To summarize the current understanding of celiac disease.
    • To highlight diagnostic methods and treatment options.
    • To identify areas for future research.

    Main Methods:

    • Literature review of existing studies on celiac disease.
    • Analysis of diagnostic criteria and treatment protocols.
    • Identification of high-risk populations and research gaps.

    Main Results:

    • Celiac disease involves immune-mediated damage to the gastrointestinal tract lining.
    • Diagnosis relies on blood tests and small intestinal biopsies.
    • A strict gluten-free diet is the sole established treatment.

    Conclusions:

    • Celiac disease is a complex autoimmune disorder requiring lifelong gluten avoidance.
    • Early diagnosis and management are crucial for patient outcomes.
    • Further investigation into environmental factors and novel treatments is necessary.

    Keywords:
    Celiac diseaseHLAdermatitis herpetiformisgluten-free dietmalabsorption

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