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Related Concept Videos

Physiology of the Heart: The Cardiac Cycle01:18

Physiology of the Heart: The Cardiac Cycle

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The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
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Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

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Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
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Cardiac Catheterization II: Right Heart Catheterization01:21

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Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
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Anatomy of the Heart01:27

Anatomy of the Heart

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The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
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Cardiac Catheterization III: Left Heart Catheterization01:24

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Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
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Lung Capacity01:47

Lung Capacity

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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Related Experiment Video

Updated: Feb 3, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
09:31

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

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Evaluation of cardiac function using heart-lung interactions.

Victoria A Bennett1, Hollmann D Aya1, Maurizio Cecconi2,3

  • 1Department of Intensive Care Medicine, St George's University Hospital NHS Foundation Trust, Blackshaw Road, London, UK.

Annals of Translational Medicine
|October 30, 2018
PubMed
Summary
This summary is machine-generated.

Heart lung interactions offer dynamic bedside assessments for cardiac function and fluid responsiveness. Understanding these physiological interactions aids clinical evaluation in conditions like left ventricular failure and ARDS.

Keywords:
Cardiachaemodynamicsrespiratory

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Area of Science:

  • Physiology
  • Critical Care Medicine
  • Cardiology

Background:

  • Heart lung interactions are crucial for evaluating cardiac function.
  • Physiology of these interactions has been a research focus.
  • Dynamic tests for fluid responsiveness utilize respiratory cycle-induced preload changes.

Purpose of the Study:

  • To summarize cardiac function assessment using heart lung interactions.
  • To introduce underlying physiology and clinical applications.
  • To provide a foundation for further exploration in the series.

Main Methods:

  • Review of clinical assessments like pulse pressure variation (PPV) and stroke volume variation (SVV).
  • Discussion of bedside tests including end expiratory occlusion and pleth variability index (PVI).
  • Exploration of echocardiography in assessing heart lung interactions.

Main Results:

  • Dynamic tests (PPV, SVV, PVI) have limitations and specific use cases.
  • Continuous positive airway pressure (CPAP) in left ventricular failure relies on heart lung interactions for afterload reduction.
  • Ventilation changes in ARDS provide insights into cardiac and respiratory systems.

Conclusions:

  • Heart lung interactions are valuable for bedside cardiac assessment.
  • Understanding these interactions improves clinical management in various critical conditions.
  • This review serves as an introduction to the clinical utility of heart lung interactions.