Related Experiment Video
Updated: Feb 3, 2026

Measuring the Interaction Force Between a Droplet and a Super-hydrophobic Substrate by the Optical Lever Method
Published on: June 14, 2019
Micromachined optical flow cell for sensitive measurement of droplets in tubing
Sammer-Ul Hassan1,2, Adrian M Nightingale3,4, Xize Niu3,4
1Faculty of Engineering and the Environment, University of Southampton, Southampton, SO17 1BJ, UK. s.hassan@soton.ac.uk.
Abstract:
Here a micromachined flow cell with enhanced optical sensitivity is presented that allows high-throughput analysis of microdroplets. As a droplet flows through multiple concatenated measurement points, the rate of enzymatic reaction in the droplet can be fully characterized without stopping the flow. Since there is no cross-talk between the droplets, the flow cell is capable of continuously measuring biochemical assays in a droplet flow and thus is suitable to be used for continuous point-of-care diagnostics monitoring. This paper describes the design and operation of the device and its validation by application to the accurate and continuous quantification of glucose concentrations using an oxidase enzymatic assay. The flow cell forms an important component in the miniaturization of chemical and bio analyzers into portable or wearable devices.
Related Concept Videos
Steady, Laminar Flow in Circular Tubes
Uterine Tubes
Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Rise of Liquid in a Capillary Tube
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...

