Related Experiment Video
Updated: Feb 3, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
County-Level Hispanic Ethnic Density and Cardiovascular Disease Mortality
Fatima Rodriguez1, Jiaqi Hu2, Kiarri Kershaw3
11 Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA.
Higher Hispanic population density is linked to increased cardiovascular disease (CVD) mortality in Hispanic communities. This association persists even after accounting for demographic and socioeconomic factors, highlighting a critical public health concern.
Area of Science:
- Public Health
- Epidemiology
- Sociology
Background:
- Hispanics are the fastest-growing ethnic group in the U.S.
- Limited understanding of how Hispanic population density affects cardiovascular disease (CVD) mortality.
- Need to investigate ethnic density as a factor in health disparities.
Purpose of the Study:
- To examine the association between Hispanic ethnic density and CVD mortality rates.
- To determine if this association differs between Hispanics and non-Hispanic whites.
- To identify factors influencing CVD mortality in ethnically concentrated areas.
Main Methods:
- Utilized county-level death data (2003-2012) from the National Center for Health Statistics.
- Included counties with over 20 Hispanic deaths (n=715).
- Applied multivariate linear regression, adjusting for demographic, socioeconomic, and healthcare factors.
Main Results:
- Overall CVD mortality rates were higher in non-Hispanic whites than Hispanics (244.8 vs. 189.0 per 100,000).
- Counties with the highest Hispanic density showed a 60% higher Hispanic mortality rate compared to the lowest.
- Increasing Hispanic ethnic density was strongly associated with higher Hispanic CVD mortality, independent of other factors.
Conclusions:
- Higher Hispanic ethnic density is associated with increased CVD mortality among Hispanics.
- County-level demographic, socioeconomic, and healthcare factors do not fully explain this elevated mortality.
- Further research is needed to understand the mechanisms driving higher CVD mortality in ethnically concentrated Hispanic communities.
Related Concept Videos
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Ethnic Identity within a Larger Culture
Overview of the Cardiovascular System
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Density
Leveling Effect

