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Updated: Feb 3, 2026

Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
Published on: May 5, 2020
A comparative retrospective study: hypoglossofacial versus masseterofacial nerve anastomosis using Sunnybrook facial
Nasser M Altamami1, Sandra Zaouche2, Delphine Vertu-Ciolino3
1Department of Otolaryngology, Facial Plastic and Cervicofacial Surgery, Edouard Herriot Hospital, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Facial paralysis reanimation via hypoglossal-to-facial or masseteric-to-facial nerve anastomosis yields comparable functional results. Masseteric-to-facial nerve anastomosis is preferred to prevent tongue atrophy.
Area of Science:
- Neurosurgery
- Plastic Surgery
- Facial Nerve Surgery
Background:
- Facial paralysis significantly impacts quality of life.
- Surgical reanimation aims to restore facial symmetry and function.
- Nerve anastomosis techniques are crucial for successful facial reanimation.
Purpose of the Study:
- To compare functional outcomes of hypoglossal-to-facial versus masseteric-to-facial nerve anastomosis for facial paralysis.
- To evaluate the efficacy of two distinct surgical reanimation techniques.
Main Methods:
- Retrospective study of 13 patients with complete facial paralysis.
- Patients underwent either masseteric-to-facial or hypoglossofacial nerve anastomosis.
- Functional results assessed using the Sunnybrook facial grading system; statistical analysis via Mann-Whitney test.
Main Results:
- No significant statistical difference in overall functional scores between the two groups.
- Hypoglossofacial anastomosis group experienced hemilingual atrophy.
- Masseteric-to-facial showed slight superiority in dynamic movements; hypoglossofacial in resting symmetry, without statistical significance.
Conclusions:
- Both hypoglossal-to-facial and masseteric-to-facial nerve anastomosis are effective for facial paralysis reanimation.
- Masseteric-to-facial nerve anastomosis is recommended to avoid hemilingual atrophy and associated complications.
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