Related Experiment Video
Updated: Feb 3, 2026

Implantation of Electrospun Vascular Grafts with Optimized Structure in a Rat Model
Published on: June 27, 2018
Formation of Neoarteries with Optimal Remodeling Using Rapidly Degrading Textile Vascular Grafts
Takuma Fukunishi1, Chin Siang Ong1, Cecillia Lui1
11 Division of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, Maryland.
Impact Statement:
We utilized innovative textile technology to create tissue-engineered vascular grafts (TEVGs) comprised exclusively of rapidly degrading material poly(glycolic acid). Our new technology led to robust neotissue formation in the TEVGs, especially extracellular matrix formation, such as elastin. In addition, the rapid degradation of the polymer significantly reduced complications, such as stenosis or calcification, as seen with the use of slow degrading polymers in the majority of previous studies for aortic small diameter TEVGs.
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