Related Experiment Video
Updated: Feb 3, 2026

Evaluation of the Spindle Assembly Checkpoint Integrity in Mouse Oocytes
Published on: September 13, 2022
[Treatment Experience of Palbociclib as a New Checkpoint Inhibitor]
Kenichi Sakurai1, Shigeru Fujisaki, Hitomi Kubota
1Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
Abstract:
We encountered a case of multiple metastases from breast cancer. The patient was administered palbociclib, which was a new checkpoint inhibitor. The patient received various chemotherapies and endocrine therapies. We observed episode of care, a harm phenomenon, and tolerability. We did not recognize adverse events more severe than Grade 3 during the 6 weeks after initiating palbociclib therapy. Diagnostic imaging showed that the metastatic lesions maintained stable disease during the 6 weeks after initiating palbociclib therapy. This case suggested that palbociclib therapy is useful for patients with metastatic breast cancer.
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