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Anvil-profiled penetrating keratoplasty: load resistance evaluation
Annalisa Canovetti1, Francesca Rossi2, Michele Rossi3
1U.O. Oculistica Asl 4, Nuovo Ospedale S. Stefano, Via Suor Niccolina Infermiera, 59100, Prato, Italy.
Biomechanics and Modeling in Mechanobiology
|November 2, 2018
Summary
The anvil profile offers superior biomechanical resistance in penetrating keratoplasty (PK) wounds compared to other laser-trephined or conventional methods. This enhanced wound stability may lead to fewer sutures and faster visual recovery for patients.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Materials Science
Background:
- Penetrating keratoplasty (PK) is a common corneal transplant procedure.
- Surgical wound integrity is crucial for successful outcomes and patient recovery.
- Optimizing wound closure can reduce complications and improve visual rehabilitation.
Purpose of the Study:
- To evaluate and compare the biomechanical load resistance of different surgical wound configurations in penetrating keratoplasty.
- To determine which wound profile offers the best resistance to internal pressure and wound prolapse.
- To assess the potential clinical benefits of superior wound configurations.
Main Methods:
- Development of 2D and 3D finite-element biomechanical models of the human cornea.
- Simulation of increasing internal pressure to assess wound misalignment and prolapse.
- Qualitative evaluation of wound resistance for mushroom, zig-zag, anvil, and conventional trephination profiles.
Main Results:
- All tested laser-trephined profiles demonstrated superior wound resistance compared to the conventional straight trephination.
- The anvil profile exhibited the highest resistance to increasing internal pressure.
- The anvil profile's mechanical strength allowed for fewer sutures and earlier suture removal.
Conclusions:
- The anvil profile provides enhanced biomechanical load resistance in penetrating keratoplasty wounds.
- This improved wound stability has the potential to facilitate reduced suture use and earlier removal.
- These advantages may contribute to expedited visual recovery in patients undergoing PK.
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