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Development and Evaluation of a Rat Model of Full-Thickness Cartilage Defects

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Endoscopic Full-Thickness Defects and Closure Techniques.

Diogo T H de Moura¹, Amit H Sachdev¹, Christopher C Thompson²

¹Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

Current Treatment Options in Gastroenterology

|November 2, 2018

Summary

This summary is machine-generated.

Endoscopic interventions are increasingly used to treat gastrointestinal transmural defects like perforations, leaks, and fistulas. Advanced endoscopic techniques and devices offer effective, minimally invasive treatment options for these complex conditions.

Keywords:

Acute leak Acute perforation Adverse events Bariatric surgery Chronic fistula Endoscopic closure Endoscopic devices Endoscopic full thickness Fistula Internal drainage Leak

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Area of Science:

Gastroenterology
Endoscopic Surgery

Background:

Gastrointestinal transmural defects, including perforations, leaks, and fistulas, are increasingly prevalent.
Therapeutic endoscopic procedures and bariatric surgery complications contribute to this rise.
Minimally invasive endoscopic treatments are gaining importance for managing these defects.

Purpose of the Study:

To review the spectrum of gastrointestinal transmural defects.
To describe current endoscopic techniques and devices for defect closure.
To highlight the evolving role of endoscopy in managing these conditions.

Main Methods:

Review of current endoscopic approaches and devices.
Categorization of transmural defects.
Description of closure, covering, and drainage techniques.

Main Results:

Endoscopic closure techniques include clips, endoloops, and sutures.
Covering techniques utilize devices like septal occluders, stents, and sealants.
Drainage methods involve endoscopic vacuum therapy and balloon dilation.

Conclusions:

Endoscopic interventions are transforming the management of gastrointestinal transmural defects.
A variety of endoscopic tools enable effective, minimally invasive treatment.
Endoscopy is becoming a primary approach for these conditions.