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Case Report: Ketamine for Pain and Depression in Advanced Cancer.
Jessica Sexton1, Rabia S Atayee1,2, Heather C Bruner1,3
11 University of San Diego Health , La Jolla, California.
Journal of Palliative Medicine
|November 2, 2018
Summary
Advanced cancer patients often experience severe pain and depression. Intravenous ketamine infusion effectively reduced neuropathic pain and resolved depression symptoms in a patient with advanced cancer.
Area of Science:
- Oncology
- Pain Management
- Psychiatry
Background:
- Patients with advanced cancer frequently experience debilitating pain and depression.
- Traditional antidepressant therapies may be limited by short prognoses in advanced cancer patients.
Observation:
- A case study involving a patient with advanced cancer presenting with neuropathic pain and severe depression.
- The patient's condition was refractory to standard treatments.
Findings:
- Intravenous ketamine infusion led to a dramatic reduction in neuropathic pain.
- The patient experienced a complete resolution of severe depression symptoms following ketamine administration.
Implications:
- Ketamine may offer a novel therapeutic option for managing refractory pain and depression in advanced cancer.
- Further research is warranted to explore the efficacy and safety of ketamine in palliative care settings.
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