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Related Experiment Video

Updated: Feb 3, 2026

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
12:24

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Published on: March 23, 2013

14.1K

Gastroparesis.

Michael Camilleri1, Victor Chedid2, Alexander C Ford3,4

  • 1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. camilleri.michael@mayo.edu.

Nature Reviews. Disease Primers
|November 3, 2018
PubMed
Summary

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This summary is machine-generated.

Gastroparesis, a gastric neuromuscular disorder, causes delayed gastric emptying and symptoms like nausea and vomiting. Diagnosis requires tests, and management focuses on nutritional support, treating causes, and symptom relief with medications.

Area of Science:

  • Gastroenterology
  • Neurology

Background:

  • Gastroparesis is characterized by delayed gastric emptying without mechanical obstruction.
  • It presents with symptoms including early satiety, nausea, vomiting, and bloating.
  • It is part of a spectrum of gastric neuromuscular dysfunction, complicating differential diagnosis with functional dyspepsia.

Purpose of the Study:

  • To define gastroparesis and its diagnostic criteria.
  • To outline the etiologies and management strategies for gastroparesis.
  • To highlight the potential of novel therapies.

Main Methods:

  • Diagnosis confirmed by measuring delayed gastric emptying using tests like gastric scintigraphy or breath testing.
  • Management involves correcting deficiencies, treating underlying causes (e.g., diabetes), and pharmacologic symptom suppression.

Related Experiment Videos

Last Updated: Feb 3, 2026

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
12:24

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Published on: March 23, 2013

14.1K
  • Research into novel agents and interventions for individualized therapy.

    • Main Results:

    • Gastroparesis is defined by delayed gastric emptying.
    • Multiple etiologies exist, including idiopathic, diabetic, iatrogenic, post-surgical, and post-viral.
    • Current management is multi-faceted, with promising new treatments on the horizon.

    Conclusions:

    • Gastroparesis requires objective measurement for diagnosis due to overlapping symptoms with other GI disorders.
    • Comprehensive management addresses nutritional status, etiology, and symptoms.
    • Individualized therapeutic approaches are expected with ongoing research and development.