A propensity score matched valuation on feasibility of low frame rate fluoroscopy during primary percutaneous

Lin Fan1, Yukun Luo2, Zhaoyang Chen2

  • 1Department of Cardiology, Institute of Coronary Heart Disease, Fujian Medical University Union Hospital, Xinquan Road 29#, Fuzhou, 350001, Fujian, China. rickfan7587@hotmail.com.

Insights

Low frame rate fluoroscopy at 7.5 frames/s significantly reduces radiation exposure during primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI) patients. This method is safe and feasible, with no increase in adverse events.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Radiation Oncology

Background:

  • Acute ST elevation myocardial infarction (STEMI) requires timely intervention.
  • Primary percutaneous coronary intervention (PPCI) is a standard treatment for STEMI.
  • Fluoroscopy is essential during PPCI but contributes to radiation exposure.

Purpose of the Study:

  • To assess the feasibility and safety of low frame rate fluoroscopy (7.5 frames/s) during PPCI.
  • To evaluate radiation dose reduction compared to standard frame rate (15 frames/s).
  • To determine the impact on procedural outcomes and adverse events.

Main Methods:

  • Retrospective analysis of 165 STEMI patients undergoing PPCI.
  • Comparison between a 7.5 frames/s fluoroscopy group and a 15 frames/s group.
  • Propensity score matching (PSM) to control for confounding factors.
  • Evaluation of radiation dose (DAP, AK), procedural time, contrast volume, and adverse events.

Main Results:

  • The 7.5 frames/s group showed a 48.9% reduction in dose-area product (DAP) and a 61.1% reduction in air kerma (AK).
  • No significant differences were observed in procedural time, fluoroscopy time, or contrast volume between groups.
  • The incidence of contrast-induced nephropathy and peri-PPCI adverse events remained comparable.

Conclusions:

  • Low frame rate fluoroscopy at 7.5 frames/s is a safe and feasible strategy for reducing radiation exposure in PPCI.
  • This approach effectively lowers radiation doses without compromising procedural efficiency or patient safety.
  • Further adoption of low frame rate fluoroscopy can benefit STEMI patients undergoing PPCI.

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