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Updated: Feb 3, 2026

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
Published on: May 26, 2015
A propensity score matched valuation on feasibility of low frame rate fluoroscopy during primary percutaneous
Lin Fan1, Yukun Luo2, Zhaoyang Chen2
1Department of Cardiology, Institute of Coronary Heart Disease, Fujian Medical University Union Hospital, Xinquan Road 29#, Fuzhou, 350001, Fujian, China. rickfan7587@hotmail.com.
Insights
Low frame rate fluoroscopy at 7.5 frames/s significantly reduces radiation exposure during primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI) patients. This method is safe and feasible, with no increase in adverse events.
Area of Science:
- Cardiology
- Medical Imaging
- Radiation Oncology
Background:
- Acute ST elevation myocardial infarction (STEMI) requires timely intervention.
- Primary percutaneous coronary intervention (PPCI) is a standard treatment for STEMI.
- Fluoroscopy is essential during PPCI but contributes to radiation exposure.
Purpose of the Study:
- To assess the feasibility and safety of low frame rate fluoroscopy (7.5 frames/s) during PPCI.
- To evaluate radiation dose reduction compared to standard frame rate (15 frames/s).
- To determine the impact on procedural outcomes and adverse events.
Main Methods:
- Retrospective analysis of 165 STEMI patients undergoing PPCI.
- Comparison between a 7.5 frames/s fluoroscopy group and a 15 frames/s group.
- Propensity score matching (PSM) to control for confounding factors.
- Evaluation of radiation dose (DAP, AK), procedural time, contrast volume, and adverse events.
Main Results:
- The 7.5 frames/s group showed a 48.9% reduction in dose-area product (DAP) and a 61.1% reduction in air kerma (AK).
- No significant differences were observed in procedural time, fluoroscopy time, or contrast volume between groups.
- The incidence of contrast-induced nephropathy and peri-PPCI adverse events remained comparable.
Conclusions:
- Low frame rate fluoroscopy at 7.5 frames/s is a safe and feasible strategy for reducing radiation exposure in PPCI.
- This approach effectively lowers radiation doses without compromising procedural efficiency or patient safety.
- Further adoption of low frame rate fluoroscopy can benefit STEMI patients undergoing PPCI.
Abstract:
The present study aimed to evaluate the feasibility of low frame rate fluoroscopy during primary percutaneous coronary intervention (PPCI) for patients with acute ST elevation myocardial infarction (STEMI). From January 2016 to December 2017, 165 consecutive patients with STEMI who underwent PPCI were retrospectively divided into two groups: the 7.5-frame group (fluoroscopy at 7.5 frames/s) and the 15-frame group (fluoroscopy at 15 frames/s), according to the frame rate of fluoroscopy used in their treatment. Reduction of radiation and safety of fluoroscopy at 7.5 frames/s were compared by a method of propensity score matching (PSM) with fluoroscopy at 15 frames/s. After PSM, there were 56 patients in each group. There were no differences in patients' baseline characteristics between two groups. The 7.5-frame protocol resulted in 48.9% reduction of DAP (9917 ± 5543 cGycm2 vs. 14766 ± 7272 cGycm2, P < 0.001) and 61.1% reduction of AK (1209 ± 562 mGy vs. 1948 ± 1105 mGy, P < 0.001) with comparable procedural time (38.1 ± 15.3 min vs. 38.8 ± 17.2 min, P = 0.830), fluoroscopy time (13.0 ± 7.2 min vs. 13.5 ± 8.1 min, P = 0.703) and contrast volume (122.3 ± 39.4 ml vs. 119.3 ± 49.4 ml, P = 0.725) to the 15-frame group. Meanwhile, this new protocol didn't increase the incidence of contrast-induced nephropathy (23.2% vs. 25.0%, OR = 0.907, 95% CI 0.381-2.157, P = 0.825) and peri-PPCI cumulative adverse events (30.4% vs. 28.6%, OR = 1.090, 95% CI 0.483-2.456, P = 0.836). In conclusion, low frame rate fluoroscopy at 7.5 frames/s is a safe and feasible strategy for reducing radiation during PPCI.
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