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Top to Tail: Anterior-Posterior Patterning Precedes Regional Nervous System Identity
Claire S Simon1, Anna-Katerina Hadjantonakis1
1Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Abstract:
In this issue, Metzis et al., demonstrate that in the development of the central nervous system, patterning along the anterior-posterior axis precedes acquisition of neural identity. This contrasts with the prevailing view that neural identity comes first, providing a new window on the origins of the brain and spinal cord.
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