Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Feb 3, 2026

Immunolabelling Myofiber Degeneration in Muscle Biopsies

Immunolabelling Myofiber Degeneration in Muscle Biopsies

Published on: December 5, 2019

Myofibers.

Dragos Cretoiu^1,2, Luciana Pavelescu², Florentina Duica¹

¹Alessandrescu-Rusescu National Institute of Mother and Child Health, Fetal Medicine Excellence Research Center Bucharest, Bucharest, Romania.

Advances in Experimental Medicine and Biology

|November 4, 2018

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Total Vaginal Hysterectomy Can Provide a Feasible Surgical Approach for Benign Conditions: A Study on Enlarged Diffuse Uterine Adenomyosis from Romania.

Healthcare (Basel, Switzerland)·2026

Same author

Atypical Pruriginous Pustular Eruption Preceding Locally Advanced Rectal Cancer: A Case Report and Gut-Skin-Tumour Axis Hypothesis.

Diagnostics (Basel, Switzerland)·2026

Same author

Special Issue "Current Research on the Role of the Gut Microbiota in Human Diseases and Health".

International journal of molecular sciences·2026

Same author

Beyond the cell membrane: subcellular organelle-targeted nanomedicines.

Chemical communications (Cambridge, England)·2026

Same author

Optimized Cardiac Health by Exercise: Cardiomyocytes and Immune Microenvironment.

Physiology (Bethesda, Md.)·2026

Same author

EV-Mediated Intracardiac Crosstalk Mitigates Doxorubicin-Induced Cardiotoxicity.

Circulation research·2026

Muscle fibers, or myofibers, are specialized cells enabling movement through excitability and contractility. This review details their organization, from neuromuscular junctions to biochemical processes, explaining muscle force generation and fiber types.

Area of Science:

Muscle Physiology
Cellular Biology

Background:

Muscle tissue comprises specialized cells called myofibers, characterized by excitability and contractility.
Myofibers generate force essential for human movement, utilizing chemical energy for contraction and relaxation.

Purpose of the Study:

To detail the organizational levels of myofibers.
To correlate structural and functional aspects of muscle tissue.
To review muscle contraction types and fiber classification.

Main Methods:

Detailed description of myofiber organization.
Correlation of structural and functional properties.
Review of neuromuscular transmission and biochemical pathways (e.g., Ca2+ release, crossbridge cycling).

Keywords:

Fast-contracting muscle fiber Myofiber Myofibril Sarcomere Skeletal muscle Slow-contracting muscle fiber

More Related Videos

DNA Electroporation, Isolation and Imaging of Myofibers

DNA Electroporation, Isolation and Imaging of Myofibers

Published on: December 23, 2015

In Vitro Differentiation of Mature Myofibers for Live Imaging

In Vitro Differentiation of Mature Myofibers for Live Imaging

Published on: January 7, 2017

Related Experiment Videos

Last Updated: Feb 3, 2026

Immunolabelling Myofiber Degeneration in Muscle Biopsies

Immunolabelling Myofiber Degeneration in Muscle Biopsies

Published on: December 5, 2019

DNA Electroporation, Isolation and Imaging of Myofibers

DNA Electroporation, Isolation and Imaging of Myofibers

Published on: December 23, 2015

In Vitro Differentiation of Mature Myofibers for Live Imaging

In Vitro Differentiation of Mature Myofibers for Live Imaging

Published on: January 7, 2017

Main Results:

Elucidation of myofiber structural organization.
Established correlations between myofiber structure and function.
Comprehensive review of muscle contraction mechanisms and fiber types.

Conclusions:

Understanding myofiber organization is key to comprehending muscle function.
The study provides a detailed overview of muscle physiology, from cellular mechanisms to fiber classification.