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Updated: Feb 3, 2026

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5-lipoxygenase-dependent biosynthesis of novel 20:4 n-3 metabolites with anti-inflammatory activity

K J Gagnon1, N Lefort1, S J Poirier2

  • 1Départment de Chimie et Biochimie, Université de Moncton, 18 Antonine-Maillet Avenue, Moncton, NB E1A 3E9, Canada.

Prostaglandins, Leukotrienes, and Essential Fatty Acids
|November 6, 2018
PubMed

Keywords:
AA, arachidonic acidADA, adenosine deaminaseALA, alpha-linolenic acidAbbreviations: 19-OH-PGB(2), 19(R)-hydroxy-prostaglandin B(2)BLT1, leukotriene B(4) receptor 1DHA, docosahexaenoic acidDPA, docosapentaenoic acidETA, eicosatetraenoic acidEicosanoidsEtOH, ethanolHpETE, hydroperoxyeicosatetraenoic acidInflammationLO, lipoxygenaseLTA(4), leukotriene A(4)LTB(4), leukotriene B(4)LTC(4), leukotriene C(4)LeukotrienesLipid mediatorsMeOH, methanolNEM, N-ethylmaleimideNeutrophilsRP-HPLC, reverse phase-HPLCSDA, stearidonic acid

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