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Updated: Feb 3, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
3D-Printed Chips: Compatibility of Additive Manufacturing Photopolymeric Substrata with Biological Applications
Megan Carve1, Donald Wlodkowic2,3
1School of Science, RMIT University, Melbourne, VIC 3083, Australia. s3437621@student.rmit.edu.au.
Abstract:
Additive manufacturing (AM) is ideal for building adaptable, structurally complex, three-dimensional, monolithic lab-on-chip (LOC) devices from only a computer design file. Consequently, it has potential to advance micro- to milllifluidic LOC design, prototyping, and production and further its application in areas of biomedical and biological research. However, its application in these areas has been hampered due to material biocompatibility concerns. In this review, we summarise commonly used AM techniques: vat polymerisation and material jetting. We discuss factors influencing material biocompatibility as well as methods to mitigate material toxicity and thus promote its application in these research fields.
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