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Impact of body mass index on CT attenuation of adrenal adenoma

Akihiro Nishie1, Yoshiki Asayama1, Kousei Ishigami1

  • 1Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

European Journal of Radiology
|November 7, 2018
PubMed

Insights

Lipid metabolism factors like BMI and cortisol influence adrenal adenoma CT scans. Pathological clear cell ratio also affects imaging, impacting diagnosis.

Area of Science:

  • Radiology
  • Endocrinology
  • Pathology

Background:

  • Adrenal adenomas (AAs) are common tumors.
  • Unenhanced CT attenuation is a key imaging feature.
  • Factors influencing AA CT attenuation require further investigation.

Purpose of the Study:

  • To determine if lipid metabolism-related factors influence unenhanced CT attenuation in adrenal adenomas.
  • To explore correlations between CT attenuation and clinicopathological factors.

Main Methods:

  • Retrospective analysis of 36 surgically confirmed adrenal adenomas.
  • Measurement of unenhanced CT attenuation for AAs and liver.
  • Assessment of clear cell ratio (CCR) and collection of clinical data including BMI, cortisol, and lipids.

Main Results:

  • CT attenuation correlated significantly with CCR, BMI, and blood cortisol levels in all patients.
  • Similar correlations were observed for patients with primary aldosteronism or non-functioning AA.

Conclusions:

  • Lipid metabolism factors, specifically BMI and blood cortisol, impact unenhanced CT attenuation of adrenal adenomas.
  • Pathological factors like CCR also play a role in AA CT attenuation.
Abstract

Keywords:
Adrenal adenomaBody mass indexCTClear cell ratioCortisol

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