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Updated: Aug 12, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
Published on: August 25, 2012
[Local hyperthermia of malignant brain tumors]
Abstract:
In glioblastoma multiforme and high-grade astrocytomas the following procedure has been implemented to try and prevent recurrence: after extirpation of the tumour its bed is lined with metal powder and the patient's head is exposed to a high-frequency magnetic field every 4 weeks. As a result the temperature is raised by induction to +45 degrees C at the boundary between metal and brain tissue. This ought to be sufficient to prevent tumour recurrence. Varied results were achieved using this technique in 103 patients.
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