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Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
Published on: July 1, 2021
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Radio-pathological Correlation of 18F-FDG PET in Characterizing Gallbladder Wall Thickening.
Vikas Gupta1, K S Vishnu2, Thakur D Yadav2
1Department of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. vikaspgi@gmail.com.
Journal of Gastrointestinal Cancer
|November 7, 2018
Summary
18F-FDG PET reliably differentiates benign from malignant gallbladder wall thickening. Combining wall thickness and SUV uptake improves diagnostic accuracy for gallbladder cancer.
Area of Science:
- Oncology
- Nuclear Medicine
- Radiology
Background:
- Gallbladder wall thickening poses diagnostic challenges with conventional imaging.
- Distinguishing benign from malignant causes is crucial for patient management.
Purpose of the Study:
- To evaluate the efficacy of 18F-FDG PET in differentiating benign and malignant gallbladder wall thickening.
- To compare 18F-FDG PET findings with histopathology.
Main Methods:
- Thirty patients with suspected gallbladder wall thickening underwent 18F-FDG PET.
- Histopathology was used as the gold standard for comparison.
- Analysis included gallbladder wall thickness and Standardized Uptake Value (SUV) on PET.
Main Results:
- 18F-FDG PET showed a sensitivity of 91% and specificity of 79% for malignancy.
- Mean gallbladder wall thickness was significantly higher in malignant cases (10.34 mm) vs. benign (6.10 mm).
- Mean SUV uptake was higher in malignant (14.26) vs. benign (4.51) lesions.
Conclusions:
- 18F-FDG PET is a reliable tool for differentiating benign and malignant gallbladder wall thickening.
- Incorporating gallbladder wall thickness and SUV values enhances diagnostic performance.
- This imaging modality aids in the accurate diagnosis of gallbladder conditions.
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