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Pericoital contraception.

Erica P Cahill1, Paul D Blumenthal

  • 1Division of Family Planning Services and Research, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA.

Current Opinion in Obstetrics & Gynecology
|November 7, 2018
PubMed
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This summary is machine-generated.

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Repeat use of emergency contraception, like levonorgestrel (LNG), is safe and effective. New on-demand oral contraceptive options show promise for meeting women's needs.

Area of Science:

  • Reproductive Health
  • Contraception Research
  • Pharmacology

Background:

  • Women express a strong interest in oral, on-demand contraceptive methods.
  • Ulipristal acetate and levonorgestrel (LNG) with meloxicam show greater ovulation disruption potential than LNG alone.
  • UK advisories on ulipristal acetate for fibroids highlight the need for more safety data.

Purpose of the Study:

  • To review the existing literature on the repeat use of emergency contraception.
  • To evaluate pericoital (during intercourse) approaches to contraception.

Main Methods:

  • Literature evaluation of studies on emergency contraception and pericoital contraception.
  • Analysis of safety and efficacy data for various on-demand contraceptive agents.

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Main Results:

  • Repeat pericoital dosing of 1.5-mg LNG is as effective as other on-demand methods and is safe, with irregular bleeding as the main side effect.
  • On-demand ulipristal acetate or meloxicam/COX-2 inhibitors show potential but require large-scale efficacy studies.
  • A significant unmet need for contraception exists, even among women with access to current options.

Conclusions:

  • On-demand oral contraception could enhance convenience and increase overall contraceptive use.
  • Further research is needed to establish the efficacy and safety of new on-demand contraceptive options.
  • Addressing the unmet need for on-demand contraception is crucial for expanding contraceptive access.