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Children with Obesity and Asthma: Which Are the Best Options for Their Management?

Lorenza Di Genova1, Laura Penta2, Anna Biscarini3

  • 1Pediatric Clinic, Department of Medical and Surgical Sciences, Università degli Studi di Perugia, Piazza Lucio Severi 1, 06132 Perugia, Italy. lory.digenova@gmail.com.

Nutrients
|November 8, 2018
PubMed

Insights

Managing childhood asthma in overweight or obese children requires targeted strategies. Evidence suggests a distinct "obese asthma" phenotype, necessitating weight management and potentially vitamin D supplementation for better control.

Area of Science:

  • Pediatric Pulmonology
  • Metabolic Disorders
  • Public Health

Background:

  • Obesity and asthma are significant global pediatric health issues, influenced by genetics and lifestyle.
  • These conditions often coexist and interact, posing complex management challenges in children.
  • A specific 'obese asthma' phenotype is increasingly recognized, characterized by severe symptoms and poor treatment response.

Purpose of the Study:

  • To review therapeutic strategies for managing asthma in pediatric patients with overweight or obesity.
  • To evaluate the current evidence on the 'obese asthma' phenotype and its clinical implications.
  • To identify potential interventions for improving asthma control in this vulnerable population.

Main Methods:

  • A narrative review of studies published between January 2008 and June 2018.
  • Literature search conducted on PubMed using keywords: 'asthma', 'overweight'/'obesity', and 'children'/'pediatric'.
  • Analysis focused on therapeutic approaches and clinical characteristics of obese pediatric asthma.

Main Results:

  • The 'obese asthma' phenotype presents with difficult-to-control asthma, increased exacerbations, and reduced response to inhaled corticosteroids.
  • Children with obesity and asthma report a lower quality of life compared to other asthma phenotypes.
  • Current evidence supports prevention-centered strategies and family-based weight management programs.

Conclusions:

  • Effective management of asthma in overweight/obese children requires addressing weight control through family support and resources.
  • Further research into vitamin D supplementation may offer additional therapeutic benefits.
  • A multifactorial intervention approach is needed to reduce the incidence and severity of pediatric obese asthma.

Keywords:
asthmaobesityoverweightvitamin Dweight loss

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