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A flexible organic reflectance oximeter array.

Yasser Khan1, Donggeon Han2, Adrien Pierre2

  • 1Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94720; yasser.khan@berkeley.edu acarias@eecs.berkeley.edu.

Proceedings of the National Academy of Sciences of the United States of America
|November 9, 2018
PubMed
Summary
This summary is machine-generated.

A new flexible, printed sensor array uses reflected light for blood oxygen saturation measurements, enabling 2D oxygenation mapping on various body parts. This advance offers improved medical sensing for chronic conditions and recovery.

Keywords:
bioelectronicsflexible electronicsorganic electronicsoximetrywearable sensors

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Area of Science:

  • Biomedical Engineering
  • Optical Sensing
  • Materials Science

Background:

  • Transmission-mode pulse oximetry is limited to transilluminated tissues and provides single-point measurements.
  • Existing sensors lack the capability for 2D oxygenation mapping.
  • There is a need for flexible, versatile sensors for broader medical applications.

Purpose of the Study:

  • To develop a flexible, printed sensor array for measuring blood oxygen saturation using reflected light.
  • To enable 2D oxygenation mapping beyond conventional sensing sites.
  • To provide mathematical models for accurate oxygenation determination.

Main Methods:

  • Fabrication of a flexible sensor array using organic light-emitting diodes and organic photodiodes.
  • Utilizing reflected light for reflectance oximetry.
  • Implementing the sensor on the forehead and adult forearms under induced ischemia.
  • Developing mathematical models for oxygenation calculation with and without pulsatile arterial signals.

Main Results:

  • Demonstrated successful oxygen saturation measurement on the forehead with a 1.1% mean error.
  • Generated 2D oxygenation maps of adult forearms.
  • Validated mathematical models for oxygenation determination in various conditions.

Conclusions:

  • The flexible, printed reflectance oximeter array offers 2D oxygenation mapping capabilities.
  • Its versatility in placement and mechanical flexibility make it suitable for diverse medical sensing applications.
  • Promising for real-time monitoring of chronic conditions and post-surgery recovery.