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Visualization of the Axonal Projection Pattern of Embryonic Motor Neurons in Drosophila
Published on: June 16, 2017
Projection Patterns of Corticofugal Neurons Associated with Vibrissa Movement
Ken-Ichi Shibata1,2, Takuma Tanaka3, Hiroyuki Hioki1,4
1Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Abstract:
Rodents actively whisk their vibrissae, which, when they come in contact with surrounding objects, enables rodents to gather spatial information about the environment. Cortical motor command of whisking is crucial for the control of vibrissa movement. Using awake and head-fixed rats, we investigated the correlations between axonal projection patterns and firing properties in identified layer 5 neurons in the motor cortex, which are associated with vibrissa movement. We found that cortical neurons that sent axons to the brainstem fired preferentially during large-amplitude vibrissa movements and that corticocallosal neurons exhibited a high firing rate during small vibrissa movements or during a quiet state. The differences between these two corticofugal circuits may be related to the mechanisms of motor-associated information processing.
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