Superwettable nanodendritic gold substrates for direct miRNA SERS detection
Yongchao Song1, Tailin Xu, Li-Ping Xu
1Research Center for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China. xutailin@ustb.edu.cn xuliping@ustb.edu.cn zhangxueji@ustb.edu.cn.
Abstract:
By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.
More Related Videos
Related Concept Videos
Directing Effect of Substituents: meta-Directing Groups
Directing Effect of Substituents: ortho–para-Directing Groups
Directional Terms
Directional Relays
Direct Motor Pathways
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
Direction of Acceleration Vectors
![Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F61682.jpg&w=3840&q=50)

