Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymers02:34

Polymers

40.9K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
40.9K
Polymers02:34

Polymers

23.3K
23.3K
Ion Channels01:19

Ion Channels

91.4K
The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.4K
Channel Rhodopsins01:11

Channel Rhodopsins

3.2K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
3.2K
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

3.8K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
3.8K
Polymer Classification: Crystallinity01:21

Polymer Classification: Crystallinity

4.0K
Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Large outbreak of group B invasive meningococcal disease in young adults in South East England, March 2026.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2026
Same author

Estimation of Effects of Filtration and Ventilation on Worker Inhalation Dose from Aerosols Produced during Nuclear Decommissioning Processes.

Health physics·2025
Same author

Parallel computing for mobilities in periodic geometries.

Physical review. E·2022
Same author

Studying first passage problems using neural networks: A case study in the slit-well microfluidic device.

Physical review. E·2022
Same author

Entropic Trapping of DNA with a Nanofiltered Nanopore.

ACS applied nano materials·2020
Same author

DNA Translocations through Nanopores under Nanoscale Preconfinement.

Nano letters·2017

Related Experiment Video

Updated: Feb 2, 2026

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

28.1K

A sequential nanopore-channel device for polymer separation.

Martin Magill1, Ed Waller2, Hendrick W de Haan1

  • 1Faculty of Science, University of Ontario Institute of Technology, 2000 Simcoe St N, Oshawa, Ontario L1H7K4, Canada.

The Journal of Chemical Physics
|November 10, 2018
PubMed
Summary
This summary is machine-generated.

This study uses simulations to show that connected nanopores can separate polymers by size. The device sorts polymers based on chain length, with different channel dimensions leading to varied separation orders.

More Related Videos

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
08:31

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

10.4K
High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.5K

Related Experiment Videos

Last Updated: Feb 2, 2026

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

28.1K
One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
08:31

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

10.4K
High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.5K

Area of Science:

  • Polymer Physics
  • Nanotechnology
  • Computational Science

Background:

  • Nanopore devices offer potential for molecular separation.
  • Understanding polymer dynamics within confined geometries is crucial for device design.

Purpose of the Study:

  • To investigate the use of connected nanopores and channels for polymer mixture separation by molecular size.
  • To analyze polymer dynamics during translocation through such a device.

Main Methods:

  • Multiscale coarse-grained simulations of semiflexible polymers.
  • Modeling polymers as bead chains near nanopores and single particles in channels.
  • Decoupling computationally intensive near-pore simulations from bulk channel simulations.
  • Mathematical deduction of polymer position distributions from single nanopore-channel pair simulations.

Main Results:

  • Observed rich polymer dynamics within the nanopore-channel system.
  • Demonstrated the potential for polymer separation based on molecular size.
  • Found that translocation time across nanopores increases with chain length.
  • Found that channel crossing time decreases with chain length due to increased exploration of channel volume by smaller chains.

Conclusions:

  • The nanopore-channel device can effectively separate polymer mixtures.
  • Polymer sorting depends on chain length and channel dimensions, allowing for tunable separation.
  • The time between translocations is a critical parameter influenced by channel geometry and polymer length.