[6-unit clinico-physical complex].

Area of Science:

• Nuclear Physics
• Medical Physics
• Radiation Oncology

Context:

• The Joint Institute for Nuclear Research (JINR) Laboratory of Nuclear Problems utilized a 680 MeV phasotron for biomedical and clinical studies.
• Previous research involved high-energy proton, negative pion, and neutron beams.

Purpose:

• To describe a new six-compartment clinico-physical facility built at the converted phasotron.
• To detail the initial physical and dosimetric characteristics of medical proton beams from the upgraded accelerator.
• To outline future radiobiological and clinical research directions using heavy nuclear particles.

Summary:

• The article presents findings from biomedical and clinical studies using high-energy particle beams (protons, negative pions, neutrons) at the JINR 680 MeV phasotron prior to its modification.
• A newly constructed six-compartment clinico-physical facility at the converted phasotron is detailed, designed for continued and expanded heavy particle research in radiation therapy.
• Initial physical and dosimetric data for medical proton beams generated by the converted accelerator and delivered to the new facility's chambers are discussed.

Impact:

• This work lays the foundation for advanced heavy particle radiation therapy.
• The new facility enables expanded investigations into the therapeutic applications of proton, pion, and neutron beams.
• Results will inform future clinical trials and optimize treatment protocols in particle therapy.