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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Multiple Eccrine Spiradenomas in a Zosteriform Distribution.

Anissa Zaouak1, Wafa Koubaa2, Azima Ben Tanfous3

  • 1Department of Dermatology, Research Unit "Genodermatoses and Cancers LR12SP03," Habib Thameur Hospital, Tunis, Tunisia; anissa_zaouak@yahoo.fr.

Skinmed
|November 11, 2018
PubMed
Summary
This summary is machine-generated.

Multiple eccrine spiradenomas, benign skin tumors, presented as painful nodules on a man's buttock and inguinal region. Surgical excision was performed for these symptomatic lesions.

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Area of Science:

  • Dermatology
  • Surgical Pathology

Background:

  • Eccrine spiradenomas are benign adnexal neoplasms originating from sweat glands.
  • Multiple lesions can occur, though they are less common than solitary forms.

Observation:

  • A 52-year-old man presented with a 28-year history of progressively enlarging, painful, blue-gray subcutaneous nodules on his left buttock and inguinal region.
  • Examination revealed multiple, well-circumscribed nodules in a zosteriform distribution, some ulcerated.
  • Computed tomography excluded bone metastases or deep invasion.

Findings:

  • Histopathology showed sharply delineated dermal nodules composed of basaloid cells in a trabecular pattern, surrounded by eosinophilic fibrous stroma.
  • No malignant transformation was observed.
  • The diagnosis was multiple eccrine spiradenomas.

Implications:

  • Surgical excision is an effective treatment for symptomatic eccrine spiradenomas.
  • Long-term follow-up is important for monitoring recurrence or new lesion development.