Related Experiment Video
Updated: Aug 14, 2026

Quantification of Hypopigmentation Activity In Vitro
Published on: March 6, 2019
[Neurologic aspects of Ito's hypomelanosis]
M Nieto Barrera1, M T Tort, T Rodríguez Caña
1Departamiento de Pediatría, Hospital Infantil Ciudad Sanitaria Virgen del Rocío, Sevilla.
Abstract:
Hypomelanosis of Ito (incontinentia pigmenti achromians) is a neurocutaneous syndrome consisting of bizarre, patterned, macular hypopigmentation over variable portions of the body surface. Associated defects in other systems occur, commonly in the central nervous system, in a significant percentage of affected individuals. Six children affected by hypomelanosis of Ito are presented. Similarities and differences between hypomelanosis and incontinentia pigmenti and systematized achromic nevus are discussed.
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