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Updated: Feb 2, 2026

Preparation of Silver-Palladium Alloyed Nanoparticles for Plasmonic Catalysis under Visible-Light Illumination
Published on: August 18, 2020
Mild dynamic kinetic resolution of amines by coupled visible-light photoredox and enzyme catalysis
Qiong Yang1, Fengqian Zhao, Na Zhang
1Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, CCNU-uOttawa Joint Research Centre, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China. szhou@mail.ccnu.edu.cn.
Abstract:
Herein, we described photoenzymatic dynamic kinetic resolution (DKR) of amines under mild conditions. The racemization of amines via a photoredox-mediated hydrogen atom transfer (HAT) protocol in conjunction with an enzyme catalyst to achieve the DKR of amines allows a variety of primary amines to be converted into a single enantiomer in high yield and with excellent enantioselectivity. Notably, this protocol can also be extended to 1,4-diamine derivatives with high levels of diastereo- and enantioselectivity.
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