Acute Kidney Injury Post Cardiac Catheterization: Does Vascular Access Route Matter?
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Updated: Feb 2, 2026

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Published on: August 9, 2013
Pradhum Ram1, Benjamin Horn1, Kevin Bryan U Lo1
1Department of Medicine, Einstein Medical Center, Philadelphia, PA 19141, United States.
Insights
Transradial access may reduce the risk of Acute Kidney Injury (AKI) in patients undergoing cardiac catheterization. This approach offers advantages for high-risk individuals, though further research is needed.
Area of Science:
- Cardiology
- Nephrology
- Interventional Cardiology
Background:
- Acute Kidney Injury (AKI) is a serious complication of cardiac catheterization, leading to longer hospital stays and higher mortality.
- The transradial approach for cardiac catheterization is increasingly utilized.
Purpose of the Study:
- To review and evaluate the impact of cardiac access site selection on the incidence of AKI post-cardiac catheterization.
- Compare outcomes between transradial and transfemoral approaches concerning AKI.
Main Methods:
- A comprehensive literature search was conducted using Medline, Google Scholar, and PubMed.
- Included studies focused on AKI following transradial and transfemoral cardiac catheterization.
Main Results:
- While AKI has multifactorial causes, individual case assessment is crucial.
- A trend suggests increased use of the transradial approach in patients with a high risk of kidney injury.
- Limitations of the transradial approach include operator experience and anatomical factors.
Conclusions:
- Transradial access presents potential benefits for high-risk patients undergoing cardiac catheterization, particularly regarding AKI.
- Larger studies are required to confirm these findings and establish the long-term trend.
Background:
Acute Kidney Injury as a complication of cardiac catheterization is associated with increased length of hospital stay and mortality. In recent years, the use of the radial artery for cardiac catheterization is increasing in frequency.
Objective:
The objective of this concise review was to evaluate the method of cardiac access site and its impact on Acute Kidney Injury following cardiac catheterization.
Methods:
After a thorough search on Medline, Google Scholar and PubMed, we included all the literature relevant to Acute kidney injury following transradial and transfemoral cardiac catheterization.
Results:
While acute kidney injury was caused due to a variety of reasons, it was important to consider each case on an individual basis. We found a trend towards increased use of transradial approach in patients at high risk of developing kidney injury. However, limitations such as operator experience, anatomical challenges and so on do exist with this approach.
Conclusion:
Transradial access offers several advantages to a patient at high risk of acute kidney injury undergoing cardiac catheterization. Further large studies are needed to establish this trend in the years ahead.
Related Concept Videos
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury VI: Nursing Management
Acute Kidney Injury V: Interprofessional Care
Cardiac Catheterization II: Right Heart Catheterization
Acute Kidney Injury III: Clinical Manifestations

