Related Experiment Video
Updated: Feb 2, 2026

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
Published on: March 4, 2016
Is lymphatic reconstitution possible after meshed skin grafting?
Q Ngo1, H Suami1, L Koelmeyer1
1Australian Lymphoedema Education Research Treatment (ALERT), Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Lymphatic function can be restored after skin grafting. A study showed lymph transport across a meshed skin graft, indicating potential for lymphatic capillary retention.
Area of Science:
- Plastic Surgery
- Regenerative Medicine
- Lymphatic Research
Background:
- Lymphatic transport restoration after skin grafting is under-explored.
- Necrotizing fasciitis often requires extensive debridement and skin grafting.
Observation:
- A patient with necrotizing fasciitis received a meshed split-thickness skin graft on the lower leg.
- Indocyanine green lymphography was performed three years post-surgery.
Findings:
- Lymphatic fluid successfully traversed the meshed skin graft.
- Dye injected in the foot reached proximal native skin, crossing the graft.
Implications:
- Split-thickness skin grafts may retain lymphatic capillaries, enabling lymph transport.
- This finding suggests potential for improved reconstructive outcomes in complex wounds.
Related Concept Videos
Mesh Analysis
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Mesh Analysis with Current Sources
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
Introduction to Lymphatic and Immune System
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
Functions of the Lymphatic and Immune System
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
Mesh Analysis for AC Circuits
The process of harmonizing these impedances begins with a clear understanding of the input and output signals. Once these signals are known, the...

