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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
Imaging Features and Management of Stress, Atypical, and Pathologic Fractures
Richard A Marshall1, Jacob C Mandell1, Michael J Weaver1
1From the Departments of Radiology (R.A.M., J.C.M., A.S., B.K.) and Orthopedic Surgery (M.J.W., M.F.), Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115.
This review clarifies atraumatic fractures, including stress, atypical, and pathologic types. Understanding their distinct imaging features and etiologies is crucial for effective orthopedic management.
Area of Science:
- Radiology
- Orthopedic Surgery
- Bone Physiology
Background:
- Traumatic and atraumatic fractures present with overlapping clinical and imaging findings.
- Atraumatic fractures encompass stress, atypical femoral, and pathologic fractures, each with unique characteristics.
- Bone remodeling and biomechanics are fundamental to understanding fracture etiologies.
Purpose of the Study:
- To review the terminology, etiology, and key imaging features of atraumatic fractures.
- To differentiate between stress, atypical, and pathologic fractures based on imaging.
- To provide imaging criteria for risk stratification of impending pathologic fractures.
Main Methods:
- Review of scientific literature on atraumatic fractures.
- Analysis of bone remodeling pathways and biomechanics.
- Discussion of characteristic imaging findings across fracture types.
Main Results:
- Shared etiologies and key differences between stress, atypical, and pathologic fractures are elucidated.
- Clinically relevant imaging features guiding management are detailed.
- Imaging criteria to distinguish stress from pathologic fractures and risk-stratify neoplasms are presented.
Conclusions:
- Accurate terminology and understanding of imaging features are essential for managing atraumatic fractures.
- Imaging plays a critical role in differentiating fracture types and guiding orthopedic treatment.
- Proximal femur serves as a model for understanding atraumatic fractures throughout the skeleton.
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