Trends in Patch Testing With the Mayo Clinic Standard Series, 2011-2015
Kevin K Veverka, Matthew R Hall1, James A Yiannias2
1Department of Dermatology, Mayo Clinic, Jacksonville, FL.
Dermatitis : Contact, Atopic, Occupational, Drug
|November 14, 2018
Summary
Patch testing identifies contact dermatitis allergens. This study analyzed Mayo Clinic data from 2011-2015, finding nickel sulfate and methylisothiazolinone were most common allergens, aligning with North American Contact Dermatitis Group findings.
Area of Science:
- Dermatology
- Allergology
- Epidemiology
Background:
- Patch testing is crucial for diagnosing contact dermatitis by identifying specific allergens.
- Standard allergen series evolve to remain relevant for current patient populations.
Purpose of the Study:
- To analyze patch test results from the Mayo Clinic's standard series between 2011 and 2015.
- To compare these findings with contemporary North American Contact Dermatitis Group (NACDG) reports.
Main Methods:
- Retrospective review of patch test reactions to standard series allergens from 2011-2015.
- Comparison of reaction rates with NACDG reports from 2011-2012 and 2013-2014.
Main Results:
- Over 60% of 2582 patients had at least one positive patch test reaction.
- The most frequent allergens included nickel sulfate hexahydrate, methylisothiazolinone, and Myroxylon pereirae resin.
- Twelve of the top 15 allergens identified matched the NACDG report's top 15.
Conclusions:
- The study highlights common allergens in contact dermatitis based on Mayo Clinic data.
- Findings show significant overlap with national data, validating the relevance of the standard series.
- Potassium dichromate, benzalkonium chloride, and methyldibromo glutaronitrile were notable allergens not consistently ranked in the NACDG top 15.
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