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Published on: June 12, 2019
Spices and Atherosclerosis
Pi-Fen Tsui1,2, Chin-Sheng Lin3, Ling-Jun Ho4
1Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan. befun1214@gmail.com.
Insights
Spices like pepper, ginger, garlic, and chili may protect against atherosclerosis. This review explores how dietary spices can help prevent cardiovascular disease through lifestyle adjustments.
Area of Science:
- Nutritional Science
- Cardiovascular Medicine
- Pharmacology
Background:
- Cardiovascular disease (CVD) is a major global health issue.
- Atherosclerosis, driven by lipid buildup and inflammation, underlies most CVD.
- Dietary spices are globally consumed and may influence atherosclerosis development.
Purpose of the Study:
- To review the protective effects of specific spice nutrients against atherosclerosis.
- To explore mechanisms, epidemiology, and clinical evidence of spices in CVD prevention.
- To provide dietary recommendations for preventing atherosclerotic CVD.
Main Methods:
- Literature review of studies on spices (pepper, ginger, garlic, onion, cinnamon, chili).
- Analysis of mechanisms, epidemiological data, and clinical trials.
- Integration of findings to inform dietary recommendations.
Main Results:
- Specific nutrients in spices demonstrate potential anti-atherosclerotic properties.
- Evidence suggests varied impacts of different spices on cardiovascular health.
- Dietary patterns incorporating these spices may reduce CVD risk.
Conclusions:
- Spices contain bioactive compounds with potential benefits for cardiovascular health.
- Dietary adjustments incorporating spices can be a strategy for preventing atherosclerotic CVD.
- Further research and personalized dietary guidance are warranted.
Abstract:
Cardiovascular disease is one of the leading causes of death and disability in the world. Atherosclerosis, characterized by lipid accumulation and chronic inflammation in the vessel wall, is the main feature of cardiovascular disease. Although the amounts of fruits and vegetables present in the diets vary by country, diets, worldwide, contain large amounts of spices; this may have positive or negative effects on the initiation and development of atherosclerosis. In this review, we focused on the potential protective effects of specific nutrients from spices, such as pepper, ginger, garlic, onion, cinnamon and chili, in atherosclerosis and atherosclerotic cardiovascular disease. The mechanisms, epidemiological analysis, and clinical studies focusing on a variety of spices are covered in this review. Based on the integrated information, we aimed to raise specific recommendations for people with different dietary styles for the prevention of atherosclerotic cardiovascular disease through dietary habit adjustments.
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