Recent Microdevice-Based Aptamer Sensors
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Updated: Feb 2, 2026

An Aptamer-based Sensor for Unchelated GadoliniumIII
Published on: January 9, 2017
Donny Nugraha Mazaafrianto1, Masatoshi Maeki2, Akihiko Ishida3
1Graduate School of Chemical Sciences and Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo 060-8628, Japan. donnymaza@eis.hokudai.ac.jp.
Abstract:
Since the systematic evolution of ligands by exponential enrichment (SELEX) method was developed, aptamers have made significant contributions as bio-recognition sensors. Microdevice systems allow for low reagent consumption, high-throughput of samples, and disposability. Due to these advantages, there has been an increasing demand to develop microfluidic-based aptasensors for analytical technique applications. This review introduces the principal concepts of aptasensors and then presents some advanced applications of microdevice-based aptasensors on several platforms. Highly sensitive detection techniques, such as electrochemical and optical detection, have been integrated into lab-on-a-chip devices and researchers have moved towards the goal of establishing point-of-care diagnoses for target analyses.
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