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Related Concept Videos

Adhesion01:14

Adhesion

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Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
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Integration by Parts: Indefinite Integrals01:26

Integration by Parts: Indefinite Integrals

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Integration by parts is a fundamental technique in calculus for evaluating integrals involving the product of two functions. It is particularly useful when direct integration is not feasible. The method is based on the product rule for differentiation, which states that the derivative of a product equals the derivative of the first function times the second, plus the first function times the derivative of the second. By integrating this identity and rearranging terms, the integration by parts...
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Integration by Parts: Definite Integrals01:23

Integration by Parts: Definite Integrals

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Definite integrals involving the product of two functions over a fixed interval can be evaluated using integration by parts. This method rewrites the integral as the difference of a product evaluated at the endpoints and a remaining definite integral that is often simpler to compute.A representative example is the definite integral of the inverse tangent function. Since there is no direct integration formula for arctan ⁡x, the integrand is rewritten as a product of arctan⁡ x and the...
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Cell Adhesion in Plants01:14

Cell Adhesion in Plants

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Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
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Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
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Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
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Tunable Adhesion for Bio-Integrated Devices.

Zhaozheng Yu1, Huanyu Cheng2,3

  • 1Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, State College, PA 16802, USA. zqy5106@psu.edu.

Micromachines
|November 15, 2018
PubMed
Summary
This summary is machine-generated.

Tunable adhesives are crucial for bio-integrated devices and tissue repair, offering adjustable adhesion for diverse biological applications. Research explores biomimetic strategies for advanced, adaptable soft tissue adhesion solutions.

Keywords:
bio-integrated devicesdry/wet conditionssoft biological tissuetissue adhesivestunable adhesion

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Area of Science:

  • Bio-integrated electronics
  • Biomaterials science
  • Adhesive technology

Background:

  • The development of bio-integrated devices and tissue adhesives necessitates tunable adhesion to soft biological tissues.
  • Adhesion strength requirements vary significantly, with strong adhesion needed for signal transfer and wound repair, and weak adhesion for easy removal and reusability.
  • Biological surfaces exhibit diverse physical and chemical properties, demanding tailored adhesive designs for specific applications.

Purpose of the Study:

  • To provide a brief overview of recent advancements in tunable adhesives.
  • To focus on the application of these adhesives in bio-integrated devices and tissue repair.
  • To highlight strategies for designing adhesives with tunable properties for soft tissues.

Main Methods:

  • Review of recent literature on tunable adhesives for biological applications.
  • Exploration of biomimetic strategies inspired by natural adhesion mechanisms.
  • Analysis of structural design and novel material synthesis approaches.

Main Results:

  • Significant progress has been made in developing tunable adhesives for soft tissues.
  • Biomimetic strategies, including structural design and new materials, are effective in creating high-performance adhesives.
  • These adhesives show potential to match or exceed the performance of natural counterparts.

Conclusions:

  • Strategic design of adhesives is essential to accommodate the varying properties of biological surfaces.
  • Tunable adhesives offer versatile solutions for bio-integrated devices and tissue repair applications.
  • Continued research inspired by nature holds promise for next-generation bio-adhesives.