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Aging and drug discovery

Daniela Bakula1, Alexander M Aliper2, Polina Mamoshina2

  • 1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.

Aging
|November 15, 2018
PubMed

Insights

Researchers are exploring molecules to extend healthspan and target age-associated diseases. A consensus is emerging that interventions in the aging process could transform healthcare and society.

Area of Science:

  • Gerontology
  • Drug Discovery
  • Biotechnology

Background:

  • Interventions extending healthspan in model organisms are known.
  • Industry and academia are investigating molecules targeting aging and age-related diseases.

Purpose of the Study:

  • Summarize discussions from the 5th Annual Aging and Drug Discovery Forum 2018.
  • Highlight progress and challenges in aging research and drug discovery.

Main Methods:

  • Review of talks and discussions from the 2018 Aging and Drug Discovery Forum.
  • Synthesis of key themes including aging mechanisms, biomarkers, interventions, and AI applications.

Main Results:

  • Aging mechanisms, conserved longevity signatures, and emerging biomarkers were discussed.
  • Potential interventions and the role of artificial intelligence in aging research were explored.
  • A consensus on the transformative potential of aging intervention molecules is emerging.

Conclusions:

  • Molecules targeting the aging process hold significant potential for transforming healthcare.
  • Collaboration between academia and industry is crucial for advancing aging research and drug discovery.
Keywords:
agingdrug discovery

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