Current Role of Active Surveillance in the Management of a Small Renal Mass

Scott G Erpelding1, Jonathan Walker1, Ramakrishna Venkatesh2

  • 11Department of Urology, University of Kentucky, Lexington, KY 40536 USA.

Insights

Small renal masses (SRMs) detection is increasing due to advanced imaging. Surveillance for SRMs ≤4 cm may become more common, particularly for patients with less aggressive tumors or significant comorbidities.

Area of Science:

  • Urology
  • Oncology
  • Radiology

Background:

  • Renal cell carcinoma (RCC) represents 3-4% of adult malignancies.
  • Over 65,000 US kidney cancer cases were diagnosed in 2013.
  • Increased abdominal imaging has led to more small renal mass (SRM) detections.

Purpose of the Study:

  • To evaluate the potential for increased surveillance of small renal masses (SRMs).
  • To analyze the role of percutaneous renal mass biopsy in managing SRMs.
  • To identify patient groups who may benefit from SRM surveillance.

Main Methods:

  • Review of recent literature on percutaneous renal mass biopsy.
  • Retrospective data analysis of small renal masses.
  • Evaluation of factors influencing surveillance decisions.

Main Results:

  • Percutaneous renal mass biopsy is gaining importance.
  • Retrospective data support surveillance for select SRMs.
  • Factors like tumor aggressiveness, patient age, and comorbidities influence management.

Conclusions:

  • Surveillance for renal masses ≤4 cm is likely to increase.
  • This approach is particularly relevant for patients with less aggressive pathology, advanced age, and multiple comorbidities.
  • Further research into optimal surveillance strategies is warranted.

Related Concept Videos

Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
547
Immune Surveillance by NK Cells and Phagocytes01:25

Immune Surveillance by NK Cells and Phagocytes

Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
8.7K
Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
469
Atomic Mass01:52

Atomic Mass

Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...
70.2K
Electrical Current01:10

Electrical Current

Electrical current is defined as the rate at which charge flows. When there is a large current present, such as that used to run a refrigerator, a large amount of charge moves through the wire in a small amount of time. If the current is small, such as that used to operate a handheld calculator, a small amount of charge moves through the circuit over a long period of time. The SI unit for current is the ampere (A), named for the French physicist André-Marie Ampère (1775–1836).
7.2K
Molar Mass01:54

Molar Mass

The identity of a substance is defined not only by the types of atoms or ions it contains but by the quantity of each type of atom or ion. For example, water, H2O, and hydrogen peroxide, H2O2, are alike in that their respective molecules are composed of hydrogen and oxygen atoms. However, because a hydrogen peroxide molecule contains two oxygen atoms, as opposed to the water molecule, which has only one, the two substances exhibit very different properties.
86.7K