Related Experiment Video
Updated: Feb 2, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Current Role of Active Surveillance in the Management of a Small Renal Mass
Scott G Erpelding1, Jonathan Walker1, Ramakrishna Venkatesh2
11Department of Urology, University of Kentucky, Lexington, KY 40536 USA.
Abstract:
Renal cell carcinoma accounts for 3-4% of adult malignant neoplasms and over 65,000 new cases of kidney cancer were diagnosed in the USA in 2013 [1, 2]. Widespread use of abdominal imaging is leading to an increased incidence in the detection of small renal masses (SRMs) among other causes [1-4]. In light of recent literature on the role of percutaneous renal mass biopsy and retrospective data analysis, surveillance for renal masses ≤4 cm is likely to become more common especially in patients with less aggressive pathology, advanced age and multiple medical comorbidities.
Insights
Small renal masses (SRMs) detection is increasing due to advanced imaging. Surveillance for SRMs ≤4 cm may become more common, particularly for patients with less aggressive tumors or significant comorbidities.
Area of Science:
- Urology
- Oncology
- Radiology
Background:
- Renal cell carcinoma (RCC) represents 3-4% of adult malignancies.
- Over 65,000 US kidney cancer cases were diagnosed in 2013.
- Increased abdominal imaging has led to more small renal mass (SRM) detections.
Purpose of the Study:
- To evaluate the potential for increased surveillance of small renal masses (SRMs).
- To analyze the role of percutaneous renal mass biopsy in managing SRMs.
- To identify patient groups who may benefit from SRM surveillance.
Main Methods:
- Review of recent literature on percutaneous renal mass biopsy.
- Retrospective data analysis of small renal masses.
- Evaluation of factors influencing surveillance decisions.
Main Results:
- Percutaneous renal mass biopsy is gaining importance.
- Retrospective data support surveillance for select SRMs.
- Factors like tumor aggressiveness, patient age, and comorbidities influence management.
Conclusions:
- Surveillance for renal masses ≤4 cm is likely to increase.
- This approach is particularly relevant for patients with less aggressive pathology, advanced age, and multiple comorbidities.
- Further research into optimal surveillance strategies is warranted.
Related Concept Videos
Principles of Disease Surveillance
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Atomic Mass
Electrical Current
Molar Mass

