Related Experiment Videos
[Recurrences of supratentorial meningiomas. Apropos of 17 cases]
G Dechambenoit1, R Ravon, J J Moreau
1Service de Neurochirurgie, CHU Dupuytren, Limoges.
Abstract:
17 cases of recurrent meningiomas observed during a 10 years period are reviewed. Meningiomas with a second localisation different from the first were excluded from the study. The tumor recurrence occurred mostly during the first five years after the surgical procedure. One case with femoral and pulmonary metastasis is described. Several factors may play a role in the genesis of the recurrence: age, sex, the tumor localisation, CT scan, the importance of the tumor ablation, the histology. In almost all cases a radiotherapy was carried out after the second surgical procedure. This retrospective study suggests the need for multifactorial prospective analysis with clinical, paraclinical and fundamental factors. Such a study would be useful to precise the natural history of meningiomas.
Insights
Recurrent meningiomas often reappear within five years of initial surgery. Further research is needed to understand factors influencing meningioma recurrence and metastasis.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Context:
- Recurrent meningiomas pose a significant clinical challenge.
- Understanding recurrence patterns is crucial for patient management.
- This study reviews 17 cases over a decade.
Purpose:
- To analyze the characteristics and potential contributing factors of recurrent meningiomas.
- To identify patterns in tumor recurrence timing and presentation.
- To highlight the need for comprehensive prospective studies.
Summary:
- The study reviewed 17 cases of recurrent meningiomas, excluding those with secondary, distinct localizations.
- Recurrence predominantly occurred within five years post-surgery.
- One case presented with femoral and pulmonary metastasis.
- Potential factors influencing recurrence include age, sex, tumor location, CT findings, extent of resection, and histology.
- Radiotherapy was administered in most cases after the second surgery.
Impact:
- This retrospective analysis underscores the need for multifactorial prospective studies.
- Such research will refine our understanding of meningioma natural history.
- Findings may inform improved surveillance and treatment strategies for meningioma patients.