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Related Concept Videos

Standard Electrode Potentials03:02

Standard Electrode Potentials

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On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
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Electrodes: Overview01:17

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Potentiometry: Membrane Electrodes01:15

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When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
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Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
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Cortical Brain Stimulation with Endovascular Electrodes.

G Gerboni, S E John, S M Ronayne

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |November 17, 2018
    PubMed
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    This study shows endovascular stentrode stimulation can safely activate brain tissue. This method offers localized neural activation, potentially improving treatments for neurological disorders.

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    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Medical Devices

    Background:

    • Neural stimulation and recording are crucial for advanced prosthetics and neurological disorder treatments.
    • The cortical vasculature offers a safe, non-craniotomy approach for chronic neural recording.
    • Clinical acceptance of neural stimulators hinges on safety and efficacy.

    Purpose of the Study:

    • To characterize endovascular cortical stimulation using subdural surface recordings.
    • To compare electrically evoked neural activity with visually evoked activity.
    • To assess the safety and efficacy of endovascular stimulation for localized neural activation.

    Main Methods:

    • Implantation of electrodes within the cortical vasculature.
    • Performing endovascular cortical stimulation.
    • Measuring neural responses using cortical subdural surface recordings.
    • Comparing electrically and visually evoked neural activity.

    Main Results:

    • Demonstrated the viability of endovascular electrodes for cortical stimulation.
    • Observed shorter response latencies for electrical stimulation compared to visual stimulation.
    • Identified distinct centers of neural activation for electrical and visual stimuli.
    • Indicated the stentrode's capability for localized neural tissue activation.

    Conclusions:

    • Endovascular cortical stimulation is feasible and can elicit neural responses.
    • This approach allows for localized neural activation, distinct from natural sensory input.
    • Endovascular stentrode technology shows promise for novel neurological therapies.