Related Experiment Video
Updated: Feb 2, 2026

Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy
Published on: December 30, 2025
Introducing a Novel Layer in Convolutional Neural Network for Automatic Identification of Diabetic Retinopathy
Abstract:
Convolutional neural networks have been widely used for identifying diabetic retinopathy on color fundus images. For such application, we proposed a novel framework for the convolutional neural network architecture by embedding a preprocessing layer followed by the first convolutional layer to increase the performance of the convolutional neural network classifier. Two image enhancement techniques i.e. 1- Contrast Enhancement 2- Contrast-limited adaptive histogram equalization were separately embedded in the proposed layer and the results were compared. For identification of exudates, hemorrhages and microaneurysms, the proposed framework achieved the total accuracy of 87.6%, and 83.9% for the contrast enhancement and contrast-limited adaptive histogram equalization layers, respectively. However, the total accuracy of the convolutional neural network alone without the prreprocessing layer was found to be 81.4%. Consequently, the new convolutional neural network architecture with the proposed preprocessing layer improved the performance of convolutional neural network.
Related Concept Videos
Convolution Properties II
The width property indicates that if the durations of input signals are T1 and T2, then the width of the output response equals the sum of both durations, irrespective of the shapes of the two functions. For instance, convolving two rectangular pulses with durations of 2 seconds and 1 second results in a function with a width of 3 seconds.
The area property asserts that the area under the...
Automatic Processing and Automatic Social Behavior
Convolution Properties I
The commutative property reveals that the input and the impulse response of an LTI (Linear Time-Invariant) system can be interchanged without affecting the output:
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

