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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Therapeutic Index01:13

Therapeutic Index

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The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...
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Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Updated: Feb 2, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
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THERAPEUTIC APPROACH IN RECURRENT INTUSSUSCEPTION OF BOWELS IN CHILDREN.

N S Bondarenko, A V Kagan, T K Nemilova

    Vestnik Khirurgii Imeni I. I. Grekova
    |November 17, 2018
    PubMed
    Summary

    For recurrent intussusception without peritonitis, conservative therapy is recommended. This approach was analyzed in 216 patients treated between 2000 and 2015.

    Area of Science:

    • Medical Science
    • Surgical Science
    • Pediatric Surgery

    Background:

    • Intussusception is a common surgical emergency in children.
    • Recurrent intussusception presents unique management challenges.
    • Timely and appropriate treatment is crucial for favorable outcomes.

    Purpose of the Study:

    • To analyze treatment outcomes for intussusception.
    • To evaluate the efficacy of conservative therapy for recurrent intussusception.
    • To identify predictors for successful conservative management.

    Main Methods:

    • Retrospective analysis of 216 patients with intussusception.
    • Data collected from 2000 to 2015.
    • Evaluation of treatment strategies including surgical and conservative approaches.

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    Main Results:

    • Conservative therapy was effective in selected cases of recurrent intussusception.
    • Absence of peritonitis symptoms was a key indicator for successful conservative treatment.
    • Surgical intervention was reserved for complicated or refractory cases.

    Conclusions:

    • Conservative management is a viable and reasonable option for recurrent intussusception when peritonitis is absent.
    • Careful patient selection is essential for optimizing conservative therapy outcomes.
    • This approach can potentially reduce surgical morbidity in pediatric patients.