Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan

Shin-Ichiro Hagiwara1, Takahiro Kudo2, Fumihiko Kakuta3

  • 1Division of General Pediatrics, Saitama Children's Medical Center, Saitama, Saitama Prefecture.

Insights

Balloon-assisted enteroscopy (BAE) is feasible in pediatric patients across multiple Japanese hospitals. This multicenter study confirms the efficacy of BAE for diagnosing gastrointestinal issues in children.

Area of Science:

  • Pediatric Gastroenterology
  • Endoscopy
  • Medical Devices

Background:

  • Balloon-assisted enteroscopy (BAE) benefits in pediatric patients are increasingly recognized.
  • Previous BAE data in children primarily comes from single-institution experiences.
  • Multi-institutional validation is crucial for establishing pediatric BAE feasibility.

Purpose of the Study:

  • To evaluate the feasibility and efficacy of pediatric balloon-assisted enteroscopy (BAE).
  • To assess BAE performance across multiple tertiary referral centers in Japan.
  • To document diagnostic yield and safety of BAE in pediatric patients.

Main Methods:

  • Prospective, multi-institutional observational study.
  • Inclusion of pediatric patients (<18 years) undergoing BAE (double-balloon or single-balloon).
  • Data collection via standardized questionnaire from April 2014 to March 2017.

Main Results:

  • 79 pediatric patients (96 procedures) were enrolled.
  • BAE was performed via antegrade and retrograde routes, with the youngest patient aged 1.6 years.
  • Overall diagnostic yield for rectal bleeding and abdominal pain was 48%; severe adverse events occurred in 2 patients (hemorrhage, pancreatitis).

Conclusions:

  • This study confirms the efficacy of balloon-assisted enteroscopy in pediatric patients.
  • BAE is a feasible and valuable diagnostic tool in pediatric gastroenterology.
  • Multi-center data supports the broader application of BAE in pediatric care.
Abstract

Related Concept Videos

Survey Safety01:28

Survey Safety

Surveying near highways, rough terrain, or power lines involves significant risks. Working along highways is particularly dangerous and requires the use of warning signs and flagmen. It is safest to avoid working directly on roads and use offsets whenever possible. When highway work is unavoidable, it must follow all safety guidelines. Surveyors should wear bright clothing, such as orange reflective vests, to ensure visibility to motorists, coworkers, and hunters. In construction zones, wearing...
396
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
349
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
564
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
345
Household Wiring And Electrical Safety01:13

Household Wiring And Electrical Safety

Companies that supply power to most modern households use three conductors, typically called a three-wire line. While one is neutral, the other two are both at 120 V but with opposite polarity, giving a voltage of 240 V between them. With a three-wire line, high-power appliances that require 240 V, such as electric stoves and clothes dryers, are linked between the two hot lines. 120 V appliances can be connected between the neutral and either of the hot lines. The neutral side, which is always...
1.7K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
587