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Change in functional status among children treated in the intensive care unit after injury
Omar Z Ahmed1, Richard Holubkov, J Michael Dean
1From the Children's National Medical Center, Washington, DC 20010 (O.Z.A., R.S.B., M.M.P.); University of Utah School of Medicine, Salt Lake City, Utah 84108 (R.H., J.M.D.); Children's Hospital Colorado, Aurora, Colorado (T.D.B.); Children's Hospital of Michigan, Detroit, Michigan (K.L.M.); Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (R.A.B.); Children's Hospital Los Angeles, Los Angeles, California (C.J.L.N.); and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (J.C.).
Insights
The Functional Status Scale (FSS) effectively measures morbidity in injured children, showing higher scores correlate with increased injury severity. This supports its use for assessing pediatric trauma outcomes.
Area of Science:
- Pediatric Trauma Care
- Clinical Outcome Measurement
- Morbidity Assessment
Background:
- Pediatric trauma mortality is declining, necessitating better morbidity assessment tools.
- The Functional Status Scale (FSS) is a validated tool for assessing function in critically ill children.
- Evaluating the FSS for overall pediatric injury morbidity is crucial.
Purpose of the Study:
- To assess the Functional Status Scale (FSS) as an outcome measure for pediatric injury.
- To determine the association between injury profiles and the development of morbidity in children.
- To evaluate the FSS's utility in quantifying functional decline after trauma.
Main Methods:
- Retrospective analysis of 553 injured children surviving to discharge.
- Defined morbidity as changes in FSS domains (≥2) or overall FSS (≥3) from pre-injury to discharge.
- Analyzed associations between injury characteristics (AIS severity, body regions) and FSS-defined morbidity.
Main Results:
- New domain and overall morbidity were observed in 17.0% and 11.0% of patients, respectively.
- Morbidity correlated with increased number of injured body regions, severe head/spine injuries, and moderate lower extremity injuries.
- Severe spine and lower extremity injuries had the greatest impact, particularly on the motor domain.
Conclusions:
- Increased Functional Status Scale (FSS) morbidity is linked to greater injury severity in children.
- The FSS is a valuable metric for assessing outcomes in pediatric trauma patients.
- Findings support FSS utilization for evaluating treatment impact and functional recovery.
Background:
Because pediatric trauma-related mortality continues to decline, metrics assessing morbidity are needed to evaluate the impact of treatment after injury. Based on its value for assessing children with traumatic brain injuries and other critical illnesses, Functional Status Scale (FSS), a tool that measures function in six domains (communication, feeding, mental, motor, sensory, and respiratory), was evaluated as an outcome measure for the overall population of injured children.
Methods:
Children with at least one injury (Abbreviated Injury Scale [AIS] severity ≥1) surviving to discharge between December 2011 and April 2013 were identified in a previous study of intensive care unit admissions. Morbidity was defined as additional morbidity in any domain (domain FSS change ≥2 or 'new domain morbidity') and additional overall morbidity (total FSS change ≥3) between preinjury status and discharge. Associations between injury profiles and the development of morbidity were analyzed.
Results:
We identified 553 injured children, with a mean of 2.0 ± 1.9 injuries. New domain and overall morbidity were observed in 17.0% and 11.0% of patients, respectively. New domain morbidity was associated with an increasing number of body regions with an injury with AIS ≥ 2 (p < 0.001), with severe (AIS ≥ 4) head (p = 0.04) and spine (p = 0.01) injuries and with at moderately severe (AIS ≥ 2) lower extremity injuries (p = 0.01). New domain morbidity was more common among patients with severe spine and lower extremity injuries (55.6% and 48.7%, respectively), with greatest impact in the motor domain (55.6% and 43.6%, respectively). New domain morbidity was associated with increasing injury severity score, number of moderately severe injuries and number of body regions with more than a moderately severe injury (p < 0.001 for all).
Conclusions:
Higher morbidity measured by the FSS is associated with increasing injury severity. These findings support the use of the FSS as a metric for assessing outcome after pediatric injury.
Level Of Evidence:
Prognostic/Epidemiologic, level III.
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