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Updated: Feb 2, 2026

Gold Nanoparticle Synthesis
Published on: July 10, 2021
An Overview of the Synthesis of Gold Nanoparticles Using Radiation Technologies
Lucas Freitas de Freitas1, Gustavo Henrique Costa Varca2, Jorge Gabriel Dos Santos Batista3
1Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP. Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil. lucasfreitas@usp.br.
Abstract:
At a nano-level, optical properties of gold are unique and gave birth to an emerging platform of nanogold-based systems for diverse applications, because gold nanoparticle properties are tunable as a function of size and shape. Within the available techniques for the synthesis of gold nanoparticles, the radiolytic synthesis allows proper control of the nucleation process without the need for reducing agents, in a single step, combined or not with simultaneous sterilization. This review details and summarizes the use of radiation technologies for the synthesis and preparation of gold nanoparticles concerning fundamental aspects, mechanism, current pathways for synthesis and radiation sources, as well as briefly outlines final applications and some toxicity aspects related to nanogold-based systems.
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