Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Single-Cell and Spatial Omics Uncover Disease-Specific Synovial Landscapes in Rheumatoid and Psoriatic Arthritis.

The Journal of rheumatology·2026

Same author

Hispanic and Latino Ethnicity and Acculturation: Influences on Skin Cancer Prevention Attitudes and Behaviors.

The Journal of clinical and aesthetic dermatology·2026

Same author

Pathogenesis of psoriasis and psoriatic arthritis: Insights from animal models and single-cell and spatial transcriptomic analyses of skin, synovium and entheses.

Best practice & research. Clinical rheumatology·2026

Same author

Trigeminal trophic syndrome presenting as Morgellons disease with a 2-year delay in diagnosis.

JAAD case reports·2026

Same author

Pruritus of Unknown Origin Treated With Aripiprazole.

International journal of dermatology·2026

Same author

CD3+ immune cell endotypes are associated with PsA disease phenotype and response to advanced therapy: an integrated mass cytometry and proteomics cohort study.

Annals of the rheumatic diseases·2025

Same journal

Letter to the editor in reply to "Ethics of Rising Trends in Dermatology Publications Using Large-Scale Databases".

Clinics in dermatology·2026

Same journal

Ethics of suggesting image-guided superficial radiation therapy on the pathology report.

Clinics in dermatology·2026

Same journal

Tanorexia: The Psychodermatology of Compulsive Tanning.

Clinics in dermatology·2026

Same journal

Ear manifestations of connective tissue diseases: A dermatologic, histopathologic, and clinicopathologic review.

Clinics in dermatology·2026

Same journal

Discovery of an intravenous drug injection site: A meticulous cutaneous examination provides the forensic dermatologic clue to a diagnosis of homicide.

Clinics in dermatology·2026

Same journal

Sherlock Holmes and the mystery of the deadly diet.

Clinics in dermatology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

Psoriasis: Psychosomatic, somatopsychic, or both?

Chase W Kwon¹, Richard G Fried², Yasmine Nousari³

¹Department of Dermatology, University of Rochester Medical Center, Rochester, New York, USA.

Clinics in Dermatology

|November 18, 2018

Summary

This summary is machine-generated.

Stress significantly impacts psoriasis development and flares. Targeting stress pathways offers new therapeutic avenues for managing this chronic inflammatory skin condition.

More Related Videos

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

Related Experiment Videos

Last Updated: Feb 2, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

Published on: August 8, 2025

Area of Science:

Dermatology
Psychoneuroimmunology
Inflammation Research

Background:

Psoriasis is a chronic inflammatory skin disease with significant psychiatric links.
Psychosocial distress is increasingly recognized as a trigger for psoriasis flares.
The stress response may directly influence psoriasis pathogenesis.

Purpose of the Study:

To review the evidence linking stress and psoriasis.
To explore the neuro-immunological mechanisms involved in stress-induced psoriasis flares.
To discuss novel therapeutic strategies targeting the stress response in psoriasis management.

Main Methods:

Review of experimental studies and clinical observations.
Analysis of research on neuromodulators and their role in neurogenic inflammation.
Examination of preliminary human trials and animal studies on stress interventions.

Main Results:

High-quality data confirm stress's critical role in psoriasis pathogenesis.
Some patients may have impaired cortisol response to stress, worsening psoriasis.
Neuromodulators like substance P and NGF are implicated in stress-mediated psoriasis flares.

Conclusions:

Stress response pathways are key targets for novel psoriasis therapies.
Psychosocial interventions and neuropeptide targeting show therapeutic promise.
Understanding the neuro-immune axis is crucial for effective psoriasis management.