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A Versatile Model of Hard Tick Infestation on Laboratory Rabbits
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Delusional infestation versus Morgellons disease.

Sara A Hylwa1, Sanna D Ronkainen2

  • 1Departments of Dermatology, Hennepin County Medical Center, Minneapolis, Minnesota, USA; University of Minnesota Medical School, Minneapolis, Minnesota, USA.

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Delusional infestation, including Morgellons disease, lacks evidence of external pathogens or infections. Treatment primarily involves antipsychotics, though patient adherence can be difficult.

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Area of Science:

  • Psychiatry
  • Dermatology
  • Infectious Diseases

Background:

  • Delusional infestation involves a false belief of being infested with pathogens.
  • Morgellons disease, a subset of delusional infestation, is characterized by perceived infestation with fibers or filaments.
  • Patients often reject psychiatric explanations, suspecting organic conditions or infections like Lyme disease.

Purpose of the Study:

  • To investigate the scientific basis of Morgellons disease and associated symptoms.
  • To determine the presence of pathogens or infections in patients with Morgellons manifestations.
  • To inform diagnostic and treatment approaches for delusional infestation.

Main Methods:

  • A large-scale study was conducted by the Centers for Disease Control and Prevention (CDC).
  • Patients presenting with Morgellons clinical manifestations were examined.
  • Microbiologic and clinical evidence was assessed to identify pathogens or infections.

Main Results:

  • The study found no evidence of fibers within the skin of patients.
  • No association was found between Morgellons manifestations and any infection, including Lyme disease.
  • Findings support the classification of Morgellons as a form of delusional infestation.

Conclusions:

  • Delusional infestation, including Morgellons disease, is not supported by evidence of external pathogens or infections.
  • Antipsychotic medication is the primary treatment for delusional infestation.
  • Challenges in patient adherence to antipsychotic treatment require further attention.