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Short-term neurological outcomes in ischemic and hemorrhagic pediatric stroke

Tuğçe Aksu Uzunhan1, Nur Aydinli2, Mine Çalişkan2

  • 1Division of Pediatric Neurology, University of Health Sciences Okmeydanı Training and Research Hospital, Istanbul, Turkey.

Pediatrics International : Official Journal of the Japan Pediatric Society
|November 19, 2018
PubMed

Insights

Pediatric stroke, including arterial ischemic stroke (AIS), cerebral sinovenous thrombosis (CSVT), and hemorrhagic stroke (HS), often leads to poor short-term neurological outcomes, with CSVT showing the worst prognosis.

Area of Science:

  • Neurology
  • Pediatric Medicine
  • Vascular Neurology

Background:

  • Pediatric stroke encompasses arterial ischemic stroke (AIS), cerebral sinovenous thrombosis (CSVT), and hemorrhagic stroke (HS).
  • Understanding short-term neurological outcomes is crucial for managing pediatric stroke cases.

Purpose of the Study:

  • To retrospectively assess short-term neurological outcomes in pediatric stroke.
  • To analyze outcomes based on patient characteristics and stroke type.

Main Methods:

  • Retrospective evaluation of children (28 days-18 years) with AIS, CSVT, and HS from 2007-2013.
  • Short-term prognosis defined by neurological findings within the first 3 months, assessed using the modified Rankin scale.

Main Results:

  • AIS affected 62% of patients, with Moya moya syndrome being common; 39% had poor prognosis.
  • Hemorrhagic stroke (HS) occurred in 23% of cases, with 70% having good prognosis.
  • Cerebral sinovenous thrombosis (CSVT) comprised 15% of cases, frequently linked to hypercoagulability, and had the highest mortality (25%) and poorest prognosis (62.5%).

Conclusions:

  • Pediatric stroke is associated with a significant rate of poor short-term prognosis.
  • Cerebral sinovenous thrombosis (CSVT) presents the worst prognosis among pediatric stroke types.
  • Detailed patient and etiological data, including thrombosis panels, are essential for understanding and managing pediatric stroke.
Abstract

Keywords:
childprognosisrisk factorstroketherapeutics

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