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Updated: Feb 2, 2026

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
Pulmonary Hypertension in Women
Veronica Franco1, John J Ryan2, Vallerie V McLaughlin3
1Division of Cardiovascular Medicine, Department of Medicine, The Ohio State University, 473 W 12th Avenue, DHLRI Suite 200, Columbus, Ohio 43210, USA.
Abstract:
Prevalence of pulmonary arterial hypertension (PAH) is higher in women, and the mechanism remains unclear. Prognosis is overall better for female compared with male patients with PAH. Pregnancy is associated with significant risk, mortality, and morbidity in patients with PAH; consensus guidelines recommend against pregnancy and counsel about early termination in these patients. Recent advances in treatment showed improvement in prognosis in small case reports of pregnant patients with PAH, particularly with the early use of parental prostacyclin. Education remains fundamental for women with PAH of childbearing age for pregnancy prevention as well as discussion about birth control methods.
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